NHS-sourced information. Always read the patient information leaflet (PIL) and speak to your pharmacist or GP before starting, stopping or changing this medication.

Home Medications Metformin
💊 Medication Guide Diabetes & Weight

Metformin

What is Metformin?

Metformin is a medicine used to treat Type 2 diabetes. It belongs to a group of medicines called biguanides. It is usually the first medicine prescribed when diet and exercise alone have not been enough to control blood sugar levels.

How It Works

Metformin works by:

  • Reducing the amount of glucose your liver releases into the blood
  • Helping your body respond better to insulin
  • Reducing the amount of glucose absorbed from food

Unlike some diabetes medicines, metformin does not cause weight gain and is unlikely to cause hypoglycaemia (low blood sugar) when used alone.

How to Take It

Metformin is taken as tablets, usually 2-3 times a day with or after meals to reduce stomach upset. The dose is usually started low and gradually increased. A slow-release (modified-release) version taken once daily is also available.

Common Side Effects

  • Nausea, vomiting, diarrhoea — especially when first starting treatment
  • Loss of appetite
  • A metallic taste in the mouth

Taking metformin with food or using the slow-release version can help reduce stomach side effects.

Important Precautions

  • Tell your doctor before taking metformin if you have kidney problems
  • Stop taking metformin temporarily before certain procedures or if you are unwell with dehydration
  • Long-term use can reduce vitamin B12 absorption — your doctor may check your B12 levels
Key Facts
Used For
Diabetes & Weight
⚠ About Side Effects

All medications can cause side effects, though not everyone gets them. The list below shows the most commonly reported effects. Contact your GP or pharmacist if you are concerned.

Common (may affect more than 1 in 10 people)
Full side effect information will be added shortly. Please refer to the Patient Information Leaflet (PIL) enclosed with your medication.
Less Common (may affect up to 1 in 10 people)
Full side effect information will be added shortly. Please refer to the Patient Information Leaflet (PIL) enclosed with your medication.
Rare (may affect up to 1 in 100 people)
Full side effect information will be added shortly. Please refer to the Patient Information Leaflet (PIL) enclosed with your medication.
Seek immediate medical attention if you experience signs of a serious allergic reaction: swelling of the face, lips, throat, or difficulty breathing.
🔗 Drug Interactions

Always tell your doctor and pharmacist about all medicines you take, including vitamins, supplements, and over-the-counter products. Some interactions can increase side effects or reduce how well a medicine works.

Other medicines: Detailed interaction information for this medication is being prepared. Ask your pharmacist for a medicines review.
Alcohol: Check with your pharmacist whether alcohol is safe to consume with this medication.
Food & drink: Some medications are affected by grapefruit juice or should be taken with food. Check your PIL or ask your pharmacist.
Take the missed dose as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose. Never take a double dose. Check your PIL or ask your pharmacist.
Do not stop taking your medication without speaking to your GP or pharmacist first. Some medications need to be reduced gradually to avoid withdrawal effects or a return of symptoms.
The time varies by medication. Some medicines work within hours; others (such as antidepressants) can take several weeks. Your doctor or pharmacist can advise on what to expect.
You must discuss this with your GP or midwife. Many medications require special consideration during pregnancy or breastfeeding.
Contact your pharmacist or GP. Many side effects are mild and temporary, but your doctor may be able to adjust your dose or switch you to an alternative.
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