✅ This trial is currently recruiting volunteers
If you think you might be eligible, speak to your GP or specialist about this trial before applying.
Status
Recruiting
Phase
PHASE1
Participants
ALL
Age Range
18 Years โ 80 Years
About This Trial
This study will evaluate the safety, tolerability, pharmacokinetics (PK), immunogenicity, and pharmacodynamics (PD) of single and multiple doses of RO7830698 in healthy participants and participants with chronic obstructive pulmonary disease (COPD).
Who Can Join?
Inclusion Criteria: All participants: * Body mass index (BMI) between 18 and 32 kilograms per meter square (kg/m2) * Agreement to adhere to the contraception requirements Part 1: * Absence of evidence of any active or chronic disease Part 2: * Confirmed diagnosis of COPD for > 6 months, as defined by the Global Initiative for Chronic obstructive Lung Disease (GOLD) guidelines * Using maintenance inhaled therapy that may include inhaled corticosteroids (ICS) and/or long-acting ฮฒ-agonist (LABA) and/or long-acting muscarinic antagonist (LAMA) as separate inhaler(s) or in combination preparation(s) * Current smoker or ex-smoker with a tobacco history of >= 10 pack years Exclusion Criteria: * Pregnant or breastfeeding, or planning to become pregnant during the study or within the timeframe in which contraception is required * Current or chronic history of clinically significant liver disease or known hepatic or biliary abnormalities (with the exception of Gilbert syndrome or asymptomatic…
⚠ Always speak to your doctor before applying to any clinical trial.