Recruiting
Gut & Digestion
Robotic Inflammatory Bowel Disease Development, Learning and Efficacy Study
To determine if robotic surgery can be performed for inflammatory bowel disease (IBD) patients, to ascertain the optimal robotic set up for multi-quadrant IBD operations and evaluate clinical…
🏢 University Hospitals Coventry and Warwickshire NHS Trust
📅 27 Oct 2026
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Recruiting
Cancer
Treatment Effectiveness in People With axSpA or PsA Starting Treatment With Bimekizumab, Risankizumab, Guselkumab, Upadacitinib, or a TNF Inhibitor
This observational study will target patients with axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) who have started treatment with bimekizumab, upadacitinib, risankizumab, guselkumab, or a tumour necrosis factor-alpha…
🏢 Adelphi Real World
📅 27 Oct 2026
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Recruiting
Brain & Nerves
REAL-MS: Observational Database Study of AHSCT and MS Therapies
Multiple sclerosis (MS) is a condition in which the immune system damages the brain and spinal cord. Treatments called disease-modifying therapies can reduce inflammation and disease activity. For…
🏢 Imperial College London
📅 27 Oct 2026
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Recruiting
Lung & Breathing
Remote Monitoring of Asthma in Children and Young People
The objective of this study is to determine whether healthcare data and remotely collected patient data can accurately predict asthma attacks in children and young people aged 5-17…
🏢 University of Edinburgh
📅 27 Oct 2026
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Recruiting
Lung & Breathing
Comparing Advanced Technologies to Standard Testing for the Diagnosis of Airway Disease in Hospital and Community Settings
Airway disease, such as chronic obstructive pulmonary disease (COPD), is usually diagnosed through breathing tests like spirometry. However, it requires people to blow forcefully into a machine several…
🏢 University Hospital Southampton NHS Foundation Trust
📅 27 Oct 2026
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Recruiting
Cancer
The PROFILE Study: Germline Genetic Profiling: Correlation With Targeted Prostate Cancer Screening and Treatment
Prostate cancer is now the most common cancer in men in the Western world. In the United Kingdom (UK), there were over 52,000 new cases diagnosed in 2016-2018…
🏢 Institute of Cancer Research, United Kingdom
📅 27 Oct 2026
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Recruiting
PHASE3
Cancer
A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant
Elranatamab is a bispecific antibody: binding of elranatamab to CD3-expressing T-cells and BCMA-expressing multiple myeloma cells causes targeted T-cell-mediated cytotoxicity. The main purpose of the study is to…
🏢 Pfizer
📅 27 Oct 2026
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Recruiting
PHASE1
Diabetes & Weight
A Phase 1/2a Study of WVE-007 in Adults Living With Overweight or Obesity
The purpose of this study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of ascending doses of WVE-007 when administered subcutaneously (SC) . Part A is a…
🏢 Wave Life Sciences USA, Inc.
📅 26 Oct 2026
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Recruiting
PHASE2
Gut & Digestion
A Study of How the Medicine Called “Etrasimod” Works in Children With the Gut Disease Called Ulcerative Colitis
The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment of moderately to severely active ulcerative colitis in pediatrics…
🏢 Pfizer
📅 26 Oct 2026
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Recruiting
PHASE3
Skin
A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children and Adolescent Participants With Moderate to Severe Plaque Psoriasis
The purpose of this pediatric study is to evaluate the drug levels, efficacy and safety of Deucravacitinib in children and adolescent participants aged 4 to
🏢 Bristol-Myers Squibb
📅 26 Oct 2026
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Recruiting
PHASE2
Mental Health
ALTO-207 in Adults With Treatment-resistant Depression (TRD)
The purpose of this trial is to measure depressive symptoms following treatment with ALTO-207 compared with placebo in participants with TRD.
🏢 Alto Neuroscience
📅 26 Oct 2026
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Recruiting
PHASE2
Heart & Circulation
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
FORTITUDE-HCM is a global, multicenter, double-blind, parallel-group, placebo-controlled Phase 2b study that will assess the efficacy and safety of ninerafaxstat compared to placebo on top of Standard of…
🏢 Imbria Pharmaceuticals, Inc.
📅 26 Oct 2026
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Recruiting
Heart & Circulation
Mechanisms of Myocardial Injury and Ischemia in Patients With Rapid Atrial Fibrillation
The goal of this observational study is to better understand the role of measuring troponin (a protein measured by a blood test) and coronary imaging in patients presenting…
🏢 University of Edinburgh
📅 26 Oct 2026
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Recruiting
Diabetes & Weight
Efficacy and Safety of a Nitric Oxide Generating Dressing for Diabetic Foot Ulcers (ONWARD)
Real world evidence study on the performance and safety of a nitric oxide generating dressing on the treatment of diabetic foot ulcers
🏢 ConvaTec Inc.
📅 26 Oct 2026
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Recruiting
PHASE2
Cancer
A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma
This is a multi-center, open label, phase II study of tebentafusp in patients with unresectable or metastatic clear cell sarcoma (CCS).
🏢 Sarcoma Alliance for Research through Collaboration
📅 26 Oct 2026
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Recruiting
PHASE3
Cancer
MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia Vera
The trial will be a phase III, randomised-controlled, multi-centre, international, open-label trial consisting of ruxolitinib versus best available therapy, where best available therapy is a choice of interferon…
🏢 University of Birmingham
📅 26 Oct 2026
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Recruiting
PHASE3
A Study to See if Tolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)
To evaluate the pharmacodynamics and safety of tolvaptan in pediatric subjects with ARPKD
🏢 Otsuka Pharmaceutical Development & Commercialization, Inc.
📅 23 Oct 2026
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Recruiting
PHASE2
Brain & Nerves
Prevent Cognitive Decline in GBA-associated Parkinson’s Disease
This is a proof-of-concept trial to investigate the efficacy of prasinezumab to slow or prevent cognitive decline in people with Parkinson's disease carrying a severe mutation in the…
🏢 University Hospital Tuebingen
📅 23 Oct 2026
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Recruiting
PHASE2
Brain & Nerves
A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer’s Disease
This is a randomized, placebo-controlled Phase 2 study to evaluate the efficacy and safety of SAR448851 in early Alzheimer's disease (AD) participants. The purpose of this study is…
🏢 Sanofi
📅 23 Oct 2026
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